Marvel's Midnight Suns is a tactical role-playing game developed by Firaxis Games and published by 2K Games. The game is set in the Marvel Universe and features a blend of strategy, role-playing, and card-based combat mechanics. In the game, players take on the role of "The Hunter," a customisable original character, and lead a team of Marvel superheroes. The story revolves around battling the demonic forces of Lilith, the Mother of Demons, who has been resurrected by the nefarious group Hydra. The gameplay involves strategic, turn-based combat, where players use a deck of ability cards to perform attacks, skills, and buffs. Between missions, players can explore the Abbey, the game's hub area, where they can interact with other heroes, upgrade abilities, and make decisions that affect the story and character relationships.

Hydra scientist Doctor Faustus resurrects Lilith, hoping to use her to help Hydra conquer the world. Six months later, the "Midnight Sun" approaches Earth, destabilizing magic and heralding the return of Lilith's master, Chthon. Doctor Strange, Tony Stark, and Carol Danvers attempt to retrieve a page of the Darkhold from Johnny Blaze but are forced to retreat to the Abbey to recruit the Midnight Suns and resurrect the Hunter, Lilith's child and killer. Lilith enthrals Venom to help her abduct Wanda Maximoff and destroy Strange's mystic shield. The heroes, joined by Spider-Man, capture Faustus to learn Lilith's plans, but Hydra operative Crossbones kills him before they can get answers. Meanwhile, Lilith enthrals Bruce Banner and Wanda, using a gamma accelerator to empower them. The heroes rescue Wanda, banish Sabretooth, and destroy the Parchment, but Lilith unleashes the demonic Hulk and summons demons worldwide. The heroes confront Lilith, who reveals her plan to destroy Chthon but inadvertently allows him to possess the Hunter. The Hunter expels Chthon, and Lilith sacrifices herself to destroy the Darkhold, restoring her human form. She, the Hunter, and Chthon's realm are consumed by the Darkhold, leaving the heroes to believe they are still alive. Meanwhile, Doctor Doom seizes the Darkhold for himself, deeming the previous users "amateurs. "