Jeanne d'Arc is a tactical role-playing video game loosely based on the story of Joan of Arc and her struggles against the English occupation of France during the Hundred Years' War in the early 15th century. The game has an amount of historical accuracy when it comes to the cast of characters, and contains many who were contemporaries and allies of Joan of Arc. This contrasts starkly with the many fantasy elements of the game, such as characters possessing magical armlets that give the wearer special abilities, and the suggestion that King Henry VI of England was possessed by demons and used them to aid his armies in destroying France during the Hundred Years' War.

In the past, there was a great war between humans and demons. Five heroes created five magical armlets and used their combined power to seal the demons away. Much time has passed, and now France and England are in the midst of the Hundred Years' War. Domrémy, a small village in the Lorraine region of France, was celebrating a festival when suddenly English soldiers attacked. A village girl, Jeanne, was led by a voice from the heavens to save France. Thus begins the journey of Jeanne, and her friends Roger and Liane, in the war to free their country from the tyranny of the demon-controlled English army.