1000xRESIST is a thrilling sci-fi adventure. The year is unknown, and a disease spread by an alien invasion keeps you underground. You are Watcher. You dutifully fulfil your purpose in serving the ALLMOTHER, until the day you discover a shocking secret that changes everything. The game blends visual novel, walking simulator, and third-person exploration as you navigate nonlinear memories and unravel the mystery of what really happened—and what’s still being kept from you.

In the near future we learn we are not alone in the universe. A mysterious alien race of giant entities arrives. We call them the Occupants. They are not hostile, but it doesn’t matter. Their arrival is a death sentence. Humanity is wiped out in a matter of months, succumbing to a disease the Occupants have brought to our planet. There is one survivor, a teenage girl called Iris. Somehow she is immune.