LittleBigPlanet 2 is a puzzle platformer video game centered around user-generated content, first announced on May 8th, 2010 in the June 2010 issue of gaming magazine Game Informer. The game was developed by Media Molecule and published by Sony Computer Entertainment Europe for the PlayStation 3 console, and is the last major Little Big Planet game in the series to be produced by Media Molecule, as the sequel, Little Big Planet 3 would be produced by Sumo Digital, Tarsier Studios, and The Station. Unlike the original LittleBigPlanet which was marketed as a "Platform game", LittleBigPlanet 2 was marketed as a "Platform for Games". The game is 100% backwards compatible with all user-created content (including personal profiles) from the first game. It is a direct sequel to LittleBigPlanet, and the third game in the series. The disc also features Sackboy's Prehistoric Moves, a ModNation Racers demo, as well as a PlayStation Network tutorial video.

Players continue Sackboy's journey after the events of the first game and the portable version are brought to an end. An inter-dimensional vacuum cleaner called the Negativitron appears over the skies of LittleBigPlanet and begins to suck up its inhabitants, including Sackboy. Larry Da Vinci (Robbie Stevens), the leader of a semi-secret semi-organised group known as "The Alliance", comes to Sackboy's rescue, saving him from the Negativitron (Jeremy Mayne). The organisation is dedicated to battling with the Negativitron and defeating it before it destroys Craftworld (Alternate name for game's environment). After Sackboy passes the tests in Larry's Hideout, he tells him that they must get to Victoria Von Bathysphere's (Judy Sweeney) Laboratory, since she has built a Sackbot army for the Alliance.