A Boy and His Blob: Trouble on Blobolonia is a 1989 video game developed by Imagineering for the Nintendo Entertainment System (NES). The game was published by Absolute Entertainment in North America and Europe and by Jaleco in Japan. A Boy and His Blob follows an unnamed, male protagonist and his shapeshifting blob friend on their adventure to save the planet of Blobolonia from the clutches of an evil emperor.

A Boy and His Blob: Trouble on Blobolonia is a platform-puzzle game. The plot involves a young boy and his alien blob friend (named Blobert) on a quest to save the latter's home planet of Blobolonia, which has been taken over by an evil emperor who only allows his subjects a diet of sweets. The boy and Blobert must traverse the subways and caves beneath the Earth and gain the necessary items before traveling to Blobolonia and defeating the emperor.