Neptunia Virtual Stars is an action RPG coinciding with the 10th anniversary of the Neptunia series. This game follows the CPUs as virtual idols teaming up with Mi and Yu of MEWTRAL to save planet EMO from the invaders known as "Anti".

Enter Virtualand - a digital world that exists alongside the networks of various dimensions. Within Virtualand lies the planet EMO - a planet faced with extinction due to the a maleficent group of content destroyers known as Anti. In an act of desperation, the digital goddess of the planet Emo, Fair, sends a distress signal to other dimensions in hopes to find a savior of this planet. And the saviors that were reached? The rising VTuber stars, Mi and Yu, members of MEWTRAL, as well as the Goddesses of Gamindustri: Neptune, Noire, Blanc, and Vert! Can MEWTRAL and the Goddesses band together and save planet EMO from complete destruction?