A science-fiction action role-playing game and the fifth main entry in the Star Ocean series. Combat is real-time, letting the player control and switch between a party of up to seven characters, with cutscenes and battles designed to flow together without breaks. The game carries over series staples such as item creation and choices that shape how the story develops, including multiple endings.

Star Ocean: Integrity and Faithlessness is set on the planet Faykreed, thousands of light years from Earth, on a world that has not yet developed space travel. Fidel Camuze, a young fencer, defends his home village alongside his childhood friend Miki Sauvester. Their lives are thrown into turmoil when Faykreed makes first contact with a more advanced spacefaring civilization. Amid the upheaval, the pair take in Relia, a quiet, amnesiac girl whose past becomes tied to the events unfolding around them.